Science & technology

Identification of hh blood group

1952

The hh blood group, known as the Bombay phenotype, is a very rare blood type first identified in 1952 by Dr Y. M. Bhende in Bombay, now Mumbai. People with it lack the H antigen, from which the A and B antigens of the ABO system are built, so their red cells show no A, B or H markers and their blood looks like type O in the usual tests. Their plasma, however, contains strong antibodies against the H antigen, so they cannot receive ordinary type O blood and can be transfused safely only with blood from another person of the same type. It is much more common in parts of India than elsewhere. The discovery showed how complex the genetics of blood groups are.

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